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MOTS-c + AOD-9604 stack calculator

MOTS-c and AOD-9604 are sometimes paired as a metabolism-focused stack. Their dose scales differ a lot — MOTS-c in milligrams, AOD-9604 in micrograms — so calculate each separately below.

Last reviewed

Educational reference only. Not medical advice — follow the instructions from your clinician or pharmacy.

Per-compound reconstitution

Each compound is calculated on its own — different vials, different concentrations, different draws. Use these references, then run your exact numbers on each compound's calculator.

MOTS-c reference

U-100 units to draw for each common MOTS-c dose, by vial size, reconstituted with 2 mL of bacteriostatic water.

VialConcentration2.5 mg5 mg10 mg
5 mg2.5 mg/mL100 u(1 mL)200 u(2 mL)400 u(4 mL)
10 mg5 mg/mL50 u(0.5 mL)100 u(1 mL)200 u(2 mL)

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Educational reference only — not a dose recommendation. Units assume a U-100 insulin syringe (100 units = 1 mL on U-100). Always confirm against your own vial, diluent, and clinician or pharmacy instructions.

AOD-9604 reference

U-100 units to draw for each common AOD-9604 dose, by vial size, reconstituted with 2 mL of bacteriostatic water.

VialConcentration250 mcg300 mcg500 mcg
2 mg1 mg/mL25 u(0.25 mL)30 u(0.3 mL)50 u(0.5 mL)
5 mg2.5 mg/mL10 u(0.1 mL)12 u(0.12 mL)20 u(0.2 mL)

Swipe the table to see every dose →

Educational reference only — not a dose recommendation. Units assume a U-100 insulin syringe (100 units = 1 mL on U-100). Always confirm against your own vial, diluent, and clinician or pharmacy instructions.

Two different dose scales

MOTS-c is dosed in the multi-milligram range while AOD-9604 is dosed in micrograms, so at the same vial size and water volume their syringe units differ widely. Calculate each on its own page and dose to your own schedule.

  • MOTS-c: mg doses; AOD-9604: mcg doses
  • Different concentrations — never share a draw figure
  • Calculate each compound independently

Watching MOTS-c volume

MOTS-c doses can fill a whole 1 mL syringe at common concentrations, while AOD-9604 draws are only a few units. Use the per-compound reference tables above, and reconstitute MOTS-c with less water if its draw exceeds your syringe.

  • MOTS-c draws can reach a full 1 mL syringe
  • AOD-9604 draws are only a few units
  • Adjust MOTS-c water to keep its draw within the syringe

Frequently asked questions

Can I combine MOTS-c and AOD-9604 in one syringe?
Calculate each compound's volume separately first, because the two vials have different concentrations. Combining them afterward is a handling choice, not a math shortcut.
Why is the MOTS-c draw so much larger than AOD-9604?
MOTS-c is dosed in milligrams and AOD-9604 in micrograms, so at the same concentration MOTS-c needs far more volume. The reference tables above show each at its own concentration.
Is this stack approved for weight loss?
Both are research peptides and neither is an approved weight-loss treatment in the major markets. This page only provides the reconstitution math and makes no treatment recommendation.

Primary sources

Background references for this page. PepSync does not make clinical claims; these citations support the educational context only.

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