PT-141 dose calculator

Quick math example

A 10 mg vial mixed with 2 mL gives 5 mg/mL. A 1.75 mg dose is 0.35 mL, which equals 35 units on a U-100 syringe.

How the PT-141 calculation works

PT-141 is labelled in milligrams per vial. Concentration is the total mg divided by BAC water volume; the per-dose volume is your target divided by that concentration.

Doses are typically in the milligram range, so draws can approach a meaningful fraction of a 1 mL syringe.

• 10 mg vial = 10,000 mcg total
• 10,000 mcg / 2 mL = 5,000 mcg per mL
• 1,750 mcg target = 0.35 mL draw

PT-141 10 mg vial with 2 mL example

A 10 mg PT-141 vial mixed with 2 mL gives 5 mg/mL, or 5,000 mcg/mL.

A 1.75 mg (1,750 mcg) dose is 0.35 mL, which equals 35 units on a U-100 syringe. A 1 mg dose would be 0.2 mL (20 units).

• 10 mg / 2 mL = 5 mg/mL
• 1,750 mcg / 5,000 mcg per mL = 0.35 mL = 35 U-100 units
• 1,000 mcg / 5,000 mcg per mL = 0.2 mL = 20 U-100 units

Use less water for a smaller PT-141 draw

Because PT-141 doses are in the milligram range, the draw can take up a third of a 1 mL syringe at 5 mg/mL. Reconstituting the same 10 mg vial in 1 mL raises the concentration to 10 mg/mL.

At 10 mg/mL a 1.75 mg dose halves to 0.175 mL, or about 17-18 units — a more compact draw for the same dose.

• 10 mg / 1 mL = 10 mg/mL
• 1,750 mcg / 10,000 mcg per mL = 0.175 mL = ~18 units
• Less BAC water = higher concentration = smaller draw

Approval and prescribing context

PT-141 (Bremelanotide) is sold under different statuses by jurisdiction. In the US an approved formulation exists for a specific indication with its own dosing, while grey-market vials are often labelled for research. The calculator math does not change, but your source and prescribing context might.

Frequently asked questions

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