Use this PT-141 calculator to translate vial strength and BAC water volume into a precise draw. PT-141 (also called Bremelanotide) is approved in some jurisdictions and not others; this page focuses only on the math.
- Common vial examples
- 10 mg
- Example dose
- 1.75 mg
- Common syringe
- U-100 insulin
- Last reviewed
Quick math example
A 10 mg vial mixed with 2 mL gives 5 mg/mL. A 1.75 mg dose is 0.35 mL, which equals 35 units on a U-100 syringe.
PT-141 reconstitution reference
U-100 units to draw for each common PT-141 dose, by vial size, reconstituted with 2 mL of bacteriostatic water. Change the water volume in the calculator above to recompute for your own setup.
| Vial | Concentration | 1 mg | 1.75 mg | 2 mg |
|---|---|---|---|---|
| 10 mg | 5 mg/mL | 20 u(0.2 mL) | 35 u(0.35 mL) | 40 u(0.4 mL) |
Swipe the table to see every dose →
Educational reference only — not a dose recommendation. Units assume a U-100 insulin syringe (100 units = 1 mL on U-100). Always confirm against your own vial, diluent, and clinician or pharmacy instructions.
How the PT-141 calculation works
PT-141 is labelled in milligrams per vial. Concentration is the total mg divided by BAC water volume; the per-dose volume is your target divided by that concentration.
Doses are typically in the milligram range, so draws can approach a meaningful fraction of a 1 mL syringe.
- 10 mg vial = 10,000 mcg total
- 10,000 mcg / 2 mL = 5,000 mcg per mL
- 1,750 mcg target = 0.35 mL draw
PT-141 10 mg vial with 2 mL example
A 10 mg PT-141 vial mixed with 2 mL gives 5 mg/mL, or 5,000 mcg/mL.
A 1.75 mg (1,750 mcg) dose is 0.35 mL, which equals 35 units on a U-100 syringe. A 1 mg dose would be 0.2 mL (20 units).
- 10 mg / 2 mL = 5 mg/mL
- 1,750 mcg / 5,000 mcg per mL = 0.35 mL = 35 U-100 units
- 1,000 mcg / 5,000 mcg per mL = 0.2 mL = 20 U-100 units
PT-141 10 mg vial: units per dose (2 mL BAC water)
U-100 units to draw for each common PT-141 dose, by vial size, reconstituted with 2 mL of bacteriostatic water. Change the water volume in the calculator above to recompute for your own setup.
| Vial | Concentration | 1 mg | 1.75 mg | 2 mg |
|---|---|---|---|---|
| 10 mg | 5 mg/mL | 20 u(0.2 mL) | 35 u(0.35 mL) | 40 u(0.4 mL) |
Swipe the table to see every dose →
Educational reference only — not a dose recommendation. Units assume a U-100 insulin syringe (100 units = 1 mL on U-100). Always confirm against your own vial, diluent, and clinician or pharmacy instructions.
PT-141 10 mg dosage in units and mL
The mL and units for a PT-141 dose depend on how much BAC water went into the 10 mg vial. At the common 2 mL (5 mg/mL) every 1 mg of PT-141 is 0.2 mL, or 20 units on a U-100 syringe, so 1 mg = 20 units, 1.75 mg = 35 units and 2 mg = 40 units.
With 1 mL (10 mg/mL) each draw halves: 1 mg = 10 units, 2 mg = 20 units. With 3 mL (about 3.33 mg/mL) each draw grows: 1 mg = 0.3 mL (30 units), 2 mg = 0.6 mL (60 units). A 10 mg vial holds ten 1 mg doses or five 2 mg doses before dead-space loss.
- 10 mg / 2 mL = 5 mg/mL → 1 mg = 0.2 mL = 20 units, 2 mg = 0.4 mL = 40 units
- 10 mg / 1 mL = 10 mg/mL → 1 mg = 0.1 mL = 10 units, 2 mg = 0.2 mL = 20 units
- 10 mg / 3 mL = 3.33 mg/mL → 1 mg = 0.3 mL = 30 units, 2 mg = 0.6 mL = 60 units
Use less water for a smaller PT-141 draw
Because PT-141 doses are in the milligram range, the draw can take up a third of a 1 mL syringe at 5 mg/mL. Reconstituting the same 10 mg vial in 1 mL raises the concentration to 10 mg/mL.
At 10 mg/mL a 1.75 mg dose halves to 0.175 mL, or about 17-18 units — a more compact draw for the same dose.
- 10 mg / 1 mL = 10 mg/mL
- 1,750 mcg / 10,000 mcg per mL = 0.175 mL = ~18 units
- Less BAC water = higher concentration = smaller draw
Approval and prescribing context
PT-141 (Bremelanotide) is sold under different statuses by jurisdiction. In the US an approved formulation exists for a specific indication with its own dosing, while grey-market vials are often labelled for research. The calculator math does not change, but your source and prescribing context might.
Frequently asked questions
Is PT-141 approved as a medicine?
Why does PT-141 require a relatively large draw volume?
How do I get a smaller, easier PT-141 draw?
Can PepSync remind me of a PT-141 dose schedule?
How many units is 1 mg of PT-141 from a 10 mg vial?
Primary sources
Background references for this calculator. PepSync does not make clinical claims; these citations support the educational context only.