Melanotan 2 dosage calculator (MT2)

How the Melanotan II calculation works

Melanotan II is labelled in milligrams per vial. Concentration is total mg divided by BAC water volume; the per-dose volume is your target divided by that concentration.

Starting protocols are usually small (around 250 mcg) and increased gradually, so per-dose draws are small and benefit from a U-100 insulin syringe for readability.

• 10 mg vial = 10,000 mcg total
• 10,000 mcg / 2 mL = 5,000 mcg per mL
• 250 mcg target = 0.05 mL draw

Melanotan II 10 mg vial with 2 mL example

A 10 mg Melanotan II vial mixed with 2 mL gives 5 mg/mL, or 5,000 mcg/mL.

A 250 mcg starting dose is 0.05 mL — just 5 units on a U-100 syringe. A 500 mcg dose would be 0.1 mL, or 10 units.

• 10 mg / 2 mL = 5 mg/mL
• 250 mcg / 5,000 mcg per mL = 0.05 mL = 5 U-100 units
• 500 mcg / 5,000 mcg per mL = 0.1 mL = 10 U-100 units

Melanotan 2 dosage in units: MT2 draws from a 10 mg vial

Community protocols usually describe MT2 dosage in micrograms — a small starting dose to test tolerance, stepped up over days to a larger dose, then a less frequent maintenance dose. This page does not recommend a dose; it converts whatever target you enter. What it can show is what each commonly cited amount looks like on a U-100 syringe from a 10 mg vial.

With 2 mL of bacteriostatic water the vial is 5 mg/mL (5,000 mcg/mL), so every 100 mcg is 2 units. With 1 mL it is 10 mg/mL and every 100 mcg is 1 unit, which makes small starting doses hard to read — most people use 2 mL for that reason.

• 100 mcg = 2 units · 250 mcg = 5 units · 500 mcg = 10 units · 1 mg = 20 units (10 mg in 2 mL)
• At 10 mg/mL (10 mg in 1 mL) halve those: 250 mcg = 2.5 units, 500 mcg = 5 units
• A 10 mg vial holds forty 250 mcg doses or twenty 500 mcg doses before dead-space loss

Loading versus maintenance draws

Community protocols often use a smaller starting dose, then a maintenance dose once a target is reached. Because both come from the same vial, only the entered target changes — the concentration stays fixed until you mix a new vial.

At 5,000 mcg/mL, stepping from 250 mcg to 500 mcg simply moves the draw from 5 units to 10 units. Re-run the calculator whenever the target changes so the units stay correct.

• Same vial, same concentration — only the target changes
• 250 mcg = 5 units; 500 mcg = 10 units at 5 mg/mL
• Re-run the math each time you change the dose

Regulatory and safety context

Melanotan II is unapproved in most major markets and has been associated with skin lesions, nausea, and other adverse effects in published reports. This page only covers the calculator math; the decision to use it sits outside the scope of this tool.