Sermorelin dosage calculator

How the sermorelin calculation works

Sermorelin vials are labelled in milligrams while doses are usually discussed in micrograms. The calculator converts the vial total to mcg, divides by your BAC water volume to find concentration, then divides your target dose by that concentration.

Doses are small, so a U-100 insulin syringe makes the draw easier to read than a larger barrel.

• 5 mg vial = 5,000 mcg total
• 5,000 mcg / 2 mL = 2,500 mcg per mL
• 300 mcg target = 0.12 mL draw

Sermorelin 5 mg vial with 2 mL example

A 5 mg sermorelin vial mixed with 2 mL gives 2.5 mg/mL, or 2,500 mcg/mL.

A 300 mcg dose is 0.12 mL, which equals 12 units on a U-100 syringe; a 200 mcg dose is 0.08 mL, or 8 units. Reconstituting in 1 mL instead doubles the concentration and halves each draw.

• 5 mg / 2 mL = 2.5 mg/mL → 300 mcg = 0.12 mL = 12 units
• 5 mg / 2 mL = 2.5 mg/mL → 200 mcg = 0.08 mL = 8 units
• 5 mg / 1 mL = 5 mg/mL → 300 mcg = 0.06 mL = 6 units

Sermorelin vs other GH-releasing peptides

Sermorelin is a GHRH analogue, like tesamorelin, and is often discussed alongside the GHRP-class secretagogues such as ipamorelin. The reconstitution math is identical across all of them — only the vial sizes and typical doses differ — so if you run more than one, calculate each on its own page.

• Same concentration math as tesamorelin and ipamorelin
• Calculate each compound separately if you run several
• A consistent water volume keeps your unit counts comparable

How much BAC water for a 10 mg sermorelin vial

Sermorelin doses are a few hundred micrograms, so a 10 mg vial is very concentrated if you add only 2 mL: 200 mcg is just 4 units at 5 mg/mL. 3 mL moves the same dose to 6 units, and more water spreads it further if the vial has room. Pick the volume that puts your dose on a mark you can read, and remember a 10 mg vial holds many doses, so it has to stay usable until it is finished.

• 10 mg + 2 mL = 5 mg/mL → 200 mcg = 4 units · 500 mcg = 10 units
• 10 mg + 3 mL = 3.33 mg/mL → 200 mcg = 6 units · 500 mcg = 15 units
• 5 mg + 2 mL = 2.5 mg/mL → 200 mcg = 8 units · 300 mcg = 12 units

How to reconstitute sermorelin (5 mg mixing instructions)

Wipe both stoppers with alcohol, draw the bacteriostatic water, and let it run slowly down the inside wall of the vial instead of onto the powder. Swirl or roll gently until the solution is clear — do not shake it — then label the vial with the date and the water you added.

For a 5 mg vial, 2 mL of bacteriostatic water gives 2.5 mg/mL, so every 4 units is 100 mcg. 2.5 mL gives 2 mg/mL, where every 5 units is 100 mcg, which some people find easier to count.

• 5 mg + 2 mL = 2.5 mg/mL → 100 mcg = 4 units
• 5 mg + 2.5 mL = 2 mg/mL → 100 mcg = 5 units

Sermorelin today: compounded and research vials

Sermorelin was once an approved medicine (Geref, in 0.5 mg and 1 mg vials), but the maker discontinued it and the FDA withdrew the approvals in 2009 for reasons unrelated to safety or effectiveness. What is sold now is compounded by pharmacies, often in 3, 6 or 9 mg vials, or sold as a research peptide in 2, 5 or 10 mg vials.

Because there is no current label, there is no single shelf life after mixing: published beyond-use dates range from a few days to several weeks. For a compounded vial, the date on the pharmacy label is the one to follow; for a research vial, keep it refrigerated and protected from light.